The pathogenesis and treatment of the `Cytokine Storm' in COVID-19.
Identifieur interne : 000122 ( 2020/Analysis ); précédent : 000121; suivant : 000123The pathogenesis and treatment of the `Cytokine Storm' in COVID-19.
Auteurs : Qing Ye [République populaire de Chine] ; Bili Wang [République populaire de Chine] ; Jianhua Mao [République populaire de Chine]Source :
- The Journal of infection [ 1532-2742 ] ; 2020.
Abstract
Cytokine storm is an excessive immune response to external stimuli. The pathogenesis of the cytokine storm is complex. The disease progresses rapidly, and the mortality is high. Certain evidence shows that, during the coronavirus disease 2019 (COVID-19) epidemic, the severe deterioration of some patients has been closely related to the cytokine storm in their bodies. This article reviews the occurrence mechanism and treatment strategies of the COVID-19 virus-induced inflammatory storm in attempt to provide valuable medication guidance for clinical treatment.
DOI: 10.1016/j.jinf.2020.03.037
PubMed: 32283152
Affiliations:
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pubmed:32283152Le document en format XML
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Electronic address: maojh88@zju.edu.cn.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>National Clinical Research Center for Child Health, National Children's Regional Medical Center, the Children's Hospital, Zhejiang University School of Medicine, No 3333, Binsheng Road, Hangzhou 310052</wicri:regionArea><placeName><settlement type="city">Hangzhou</settlement><region type="province">Zhejiang</region></placeName></affiliation></author></analytic><series><title level="j">The Journal of infection</title><idno type="eISSN">1532-2742</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Cytokine storm is an excessive immune response to external stimuli. The pathogenesis of the cytokine storm is complex. The disease progresses rapidly, and the mortality is high. Certain evidence shows that, during the coronavirus disease 2019 (COVID-19) epidemic, the severe deterioration of some patients has been closely related to the cytokine storm in their bodies. This article reviews the occurrence mechanism and treatment strategies of the COVID-19 virus-induced inflammatory storm in attempt to provide valuable medication guidance for clinical treatment.</div></front></TEI><affiliations><list><country><li>République populaire de Chine</li></country><region><li>Zhejiang</li></region><settlement><li>Hangzhou</li></settlement></list><tree><country name="République populaire de Chine"><region name="Zhejiang"><name sortKey="Ye, Qing" sort="Ye, Qing" uniqKey="Ye Q" first="Qing" last="Ye">Qing Ye</name></region><name sortKey="Mao, Jianhua" sort="Mao, Jianhua" uniqKey="Mao J" first="Jianhua" last="Mao">Jianhua Mao</name><name sortKey="Wang, Bili" sort="Wang, Bili" uniqKey="Wang B" first="Bili" last="Wang">Bili Wang</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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